071 Clopidogrel and statins: Assessing a potential drug-drug interaction
نویسندگان
چکیده
منابع مشابه
comparative dna interaction studies of antiviral drug, zidovudine and its complex using different instrumental methods
هدف از این مطالعه بررسی امکان استفاده از داروهای شناخته شده در درمان سایر بیماریها به عنوان داروهای ضد سرطان است. همچنین با استفاده از این داروها در ساختمان کمپلکس فلز می توان شاخص های دارویی بدست آمده را بررسی نمود. داروی ضد ویروس ایدز(hiv)به نام زیدوودین(azt)انتخاب و.کمپلکس.محلول.در.آب[pt(azt)2]cl2سنتزو به روشهای مختلف فیزیکی و شیمیایی شناسایی گردید. بر هم کنش مقایسه ای این دارو و کمپلکس پلا...
15 صفحه اولClopidogrel and proton pump inhibitors: a new drug interaction?
Clopidogrel is a thienopyridine platelet antagonist that irreversibly inhibits the binding of adenosine diphosphate to platelet receptors, ultimately leading to inhibition of platelet aggregation. Clopidogel is a prodrug requiring hepatic bioactivation via cytochrome P450 isozymes (CYP2C19, CYP3A4, CYP3A5) to its pharmacologically active form. Inhibition of cytochrome P450 may interfere with me...
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BACKGROUND Statins are lipid-lowering agents that also exhibit pleiotropic effects in decreasing oxidative stress and inflammation. There have been several published studies reporting the use of statins in the treatment of asthma patients, but their results are not consistent. The aim of this study is to determine whether statins are beneficial for asthma administration, and explore the potenti...
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Background: Reciprocal drug interactions are among the most common causes of adverse drug reactions. We investigated the incidence and related risk factors associated with mutual drug interactions in relation to prescriptions written in the neurology wards of two major teaching hospitals in Shiraz, southern Iran. Methods: Data was collected from hand-written prescriptions on a daily basis. Mutu...
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What is the evidence? Clopidogrel is an anti-platelet drug that has been widely used to prevent strokes and heart attacks in persons at high risk. In a study reported in this issue of Rheumatology, Yamaguchi et al. [1] investigated whether clopidogrel prevented steroid-induced osteonecrosis (ON) in rabbits. Thirty-three animals received clopidogrel (5 mg/kg of body weight) mixed with normal sal...
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ژورنال
عنوان ژورنال: Archives of Cardiovascular Diseases Supplements
سال: 2012
ISSN: 1878-6480
DOI: 10.1016/s1878-6480(12)70467-6